The Center for Mucosal & Microbiome Biology is focused on bolstering the curriculum at UT Health San Antonio. We have developed the following courses for the Graduate School of Biomedical Sciences’ curriculum.
The Microbiome & the Associated Metabolites in Health and Diseases
The field of microbiome is rapidly expanding in both basic and clinical scientific research. Whether in the gut or oral cavity, the microbiome and the associated metabolites play an integral role in human health and can significantly affect disease outcomes. This course will provide an overview on the role of the microbiome and the associated metabolites in human health and disease. It will focus on clarifying the conceptual framework for understanding how microbiome, particularly gut microbiome, impact on human health and well-being. The course will also introduce students to the technical approaches and bioinformatics required to study the microbiome and the associated metabolites in the hosts.
Topics covered include:
- The concept of the microbiome and its role in human health
- The role of the microbiome and associated metabolites in different systems (e.g., oral cavity and gut-brain-axis)
- The impact of alterations to the gut microbiome by pathogenic diseases and inflammation (gut dysbiosis)
- Research strategies and multiomic approaches for working with human and murine gut microbiome (bioinformatics, transcriptomic, and metabolomic analyses)
- Animal models used to investigate the microbiome
- Modification of the gut microbiome via dietary, supplemental, and the potential for novel treatments
“We have outstanding investigators leading cutting-edge studies in many areas, including medicine, physiology, pharmacology, microbiology, and biochemistry. The Center will bring the strength and expertise of all our colleagues together. With your leadership, we will develop studies to explore the unchartered territory of microbiome and mucosal biology; and lead the field in new discoveries.”
-Manzoor Bhat, MS, PhD
Interim Vice Dean for Research
Professor and Chair, Cellular and Integrative Physiology