The Center for Mucosal & Microbiome Biology specializes in the use of the state-of-art Multiomic Approaches to create a comprehensive picture of the involved complex interplay between the microbiome and human health. Multiomics is a new research strategy to biological analyze data sets of different omic groups (transcriptome, metabolome, epigenome etc.) to correlatively create a thorough bioinformatic analysis.
The applications for multiomics are vast, ranging from elucidating the nature of host-pathogen interactions to illuminating the mechanisms behind non-communicable diseases. By combining these various “omic” approaches, scientists can analyze complex biological data to determine novel associations between biological entities, identify important biomarkers and build elaborate markers of disease and physiology.
The Center utilizes and will train faculty in the following multiomic areas:
- Transcriptomics (RNA-seq, scRNA-seq)
- Epigenomics (DNA-methylation, Chromatin Accessibility)
- Cellular Metabolomics
- Microbiome
- Microbiome-associated Metabolomics
- Bioinformatics